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Cell Biology 101 for Advanced High School Classes

This package includes Mitosis & Meiosis Explored™, our brand new interactive tutorials, which work well both as homework or as in-class exercises. Gorgeous live videos, interactive animations, simulated experiments, and lots of thought-provoking challenges and puzzles teach via inquiry and discovery instead of rote memorization. These tutorials dovetail perfectly with the student-directed, inquiry-based focus of the revised AP Biology* framework. Alignments coming soon! The package also includes our popular Osmosis and Diffusion labs, which use engaging simulated experiments to dispel common misconceptions about the molecular-level processes underlying these two fundamental processes.

The laboratories in our Cell Biology 101 package are also included in our Complete 101 Collection. If you or your colleagues also teach Advanced Biology, the school-wide Complete 101 Collection is a great choice!

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Cell Biology 101 Labs

Mitosis Explored™

We promise you have never seen a mitosis tutorial like Mitosis Explored™! By integrating stunning live video from diverse organisms, interactive animations, and simulated experiments, Mitosis Explored smashes the "memorize the stages of mitosis" mold. This tutorial uses an inquiry-driven, self-guided approach to extend students' comprehension of the mechanics of this important (but challenging to learn) process. Students are able to tinker with the machinery that drives mitosis, solve puzzles, do experiments, and receive lots of instant feedback to check their own understanding. They also explore how mitosis relates to cancer and other diseases. Key Concepts: mitosis, mitotic stages, mitotic mechanisms, mitotic errors, anueploidy, mitosis and the cell cycle

Meiosis Explored™

Meiosis Explored™ offers a refreshing new approach to teach this fascinating and fundamental (but challenging to learn!) process. Using engaging simulated experiments, puzzles, dozens of instant-feedback questions, and illuminating animations and microscopy images, Meiosis Explored investigates the how and why of meiosis rather than focusing on memorization of stages and terminology. This tutorial uses an inquiry-driven, self-directed approach that guides students through the events that take place in meiosis and elucidates why they occur in a particular order. One section makes connections with genetics, focusing on how meiosis produces variation in offspring. Another section focuses on disorders that arise from meiotic errors. The tutorial helps students actually understand the differences and similarities between meiosis and mitosis (and works well with the accompanying Mitosis Explored tutorial). Key Concepts: meiosis, meiosis and genetics, meiosis vs. mitosis, meiotic errors, haploid vs. diploid, crossing over and recombination

Diffusion

This lab confronts common misconceptions about diffusion using engaging simulated molecular-level experiments. The lab first focuses students' attention on how individual molecules move under different conditions. It then sets up a fun experiment that allows them to explore whether nerve cells could use diffusion to move materials from the cell body to the synapses at the tips of their axons. Students run races in axons of different lengths and record how long it takes for "peptide" molecules to diffuse down their length. They also run "races" between peptides that start among high concentrations of other peptides and peptides that start surrounded only by water. By the end of the lab, students not only uncover the need for cellular and organ level transport mechanisms, but also overcome some commonly held misconceptions (see our Publications page for details). Key Concepts: Diffusion; Overcoming common misconceptions; Randomness

Osmosis

This popular lab puts students in the role of a doctor providing intravenous fluids to a patient. They must compose an intravenous fluid that does not cause the patient's red blood cells to expand or shrink. Using simulated cells, students explore osmosis with no, one, two, and many solutes. In the process of exploring the underlying molecular mechanisms of osmosis and osmotic pressure, students manipulate concentrations and conduct experiments to investigate what is meant by "dynamic equilibrium" and throughout the lab use quantitative reasoning to predict experimental outcomes. See our Publications page to read how this lab successfully conquers misconceptions! One caveat: students who have trouble with ratios may need assistance. Key Concepts: Equilibrium; Osmosis; Overcoming common misconceptions

*AP is a registered trademark of the College Board, which was not involved in the production of, and does not endorse, this product.

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